The purpose of the article was to mainly understand the role of Wnt/β-catenin in the repairing of heart tissue after damage. It first gives us a lot of introduction and background information needed about heart tissue regeneration. All organism can regenerate damaged tissue but by each organism it depends on our ability which tissue we can regenerate.          Humans, cannot regenerate heart tissue. And sciencist, including Gunes Ozhan and Gilbert Weidinger were questioning how we can make that possible and be later used in regenerative therapies. Lower vertebrae animals can regenerate heart tissue, like zebrafish and newts. Other animals like neonatal mice lose their ability to do so after seven days. And after careful research scientist see that Wnt/β-catenin plays an important role of helping the regeneration of tissue by channeling Wnt proteins, β-catenin, an effector molecule, fibrosis and many other important proteins.